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Induction of Reactive Oxygen Species by Human T-Cell Leukemia Virus Type 1 Tax Correlates with DNA Damage and Expression of Cellular Senescence Marker

Human T-cell leukemia virus type 1 (HTLV-1) Tax affects cellular genomic stability and senescence. As yet, the mechanism(s) for these events caused by Tax is incompletely understood. Here, we show that Tax expression in primary human cells induces reactive oxygen species (ROS), which elicits DNA dam...

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書誌詳細
主要な著者: Kinjo, Takao, Ham-Terhune, Julia, Peloponese, Jean-Marie, Jeang, Kuan-Teh
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863840/
https://ncbi.nlm.nih.gov/pubmed/20219913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02460-09
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