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Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

BACKGROUND: It is poorly understood why many transforming proteins reportedly enhance both cell growth (transformation) and cell death (apoptosis). At first glance, the ability to transform and the ability to engender apoptosis seem to be contradictory. Interestingly, both abilities have been widely...

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Detalhes bibliográficos
Main Authors: Kasai, Takefumi, Jeang, Kuan-Teh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419724/
https://ncbi.nlm.nih.gov/pubmed/15169569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-7
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