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Induction of Reactive Oxygen Species by Human T-Cell Leukemia Virus Type 1 Tax Correlates with DNA Damage and Expression of Cellular Senescence Marker

Human T-cell leukemia virus type 1 (HTLV-1) Tax affects cellular genomic stability and senescence. As yet, the mechanism(s) for these events caused by Tax is incompletely understood. Here, we show that Tax expression in primary human cells induces reactive oxygen species (ROS), which elicits DNA dam...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kinjo, Takao, Ham-Terhune, Julia, Peloponese, Jean-Marie, Jeang, Kuan-Teh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863840/
https://ncbi.nlm.nih.gov/pubmed/20219913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02460-09
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