Downregulation of mdr-1 expression by 8-Cl-cAMP in multidrug resistant MCF-7 human breast cancer cells.

8-Cl-cAMP, a site-selective analogue of cAMP, decreased mdr-1 expression in multidrug-resistant human breast cancer cells. A sixfold reduction of mdr-1 mRNA expression by 8-Cl-cAMP began within 8 h of treatment and was associated with a decrease in the synthesis of P-glycoprotein and with an increas...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Scala, S, Budillon, A, Zhan, Z, Cho-Chung, Y S, Jefferson, J, Tsokos, M, Bates, S E
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC286382/
https://ncbi.nlm.nih.gov/pubmed/7543490
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki