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Separate Cl- conductances activated by cAMP and Ca2+ in Cl(-)-secreting epithelial cells.

We studied the cAMP- and Ca2(+)-activated secretory Cl- conductances in the Cl(-)-secreting colonic epithelial cell line T84 using the whole-cell patch-clamp technique. Cl- and K+ currents were measured under voltage clamp. Forskolin or cAMP increased Cl- current 2-15 times with no change in K+ curr...

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Detalhes bibliográficos
Main Authors: Cliff, W H, Frizzell, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54240/
https://ncbi.nlm.nih.gov/pubmed/2164213
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