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Separate Cl- conductances activated by cAMP and Ca2+ in Cl(-)-secreting epithelial cells.

We studied the cAMP- and Ca2(+)-activated secretory Cl- conductances in the Cl(-)-secreting colonic epithelial cell line T84 using the whole-cell patch-clamp technique. Cl- and K+ currents were measured under voltage clamp. Forskolin or cAMP increased Cl- current 2-15 times with no change in K+ curr...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Cliff, W H, Frizzell, R A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54240/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.13.4956
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