Cytotoxic T Cells Are the Predominant Players Providing Cross-Protective Immunity Induced by γ-Irradiated Influenza A Viruses

We previously demonstrated that a single dose of nonadjuvanted intranasal γ-irradiated influenza A virus can provide robust protection in mice against both homologous and heterosubtypic challenges, including challenge with an H5N1 avian virus strain. We investigated the mechanism behind the observed...

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Detalhes bibliográficos
Main Authors: Furuya, Yoichi, Chan, Jennifer, Regner, Matthias, Lobigs, Mario, Koskinen, Aulikki, Kok, Tuckweng, Manavis, Jim, Li, Peng, Müllbacher, Arno, Alsharifi, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863765/
https://ncbi.nlm.nih.gov/pubmed/20164231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02508-09
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