Gamma-Irradiated Influenza Virus Uniquely Induces IFN-I Mediated Lymphocyte Activation Independent of the TLR7/MyD88 Pathway

BACKGROUND: We have shown previously in mice, that infection with live viruses, including influenza/A and Semliki Forest virus (SFV), induces systemic partial activation of lymphocytes, characterized by cell surface expression of CD69 and CD86, but not CD25. This partial lymphocytes activation is me...

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Hauptverfasser: Furuya, Yoichi, Chan, Jennifer, Wan, En-Chi, Koskinen, Aulikki, Diener, Kerrilyn R., Hayball, John D., Regner, Matthias, Müllbacher, Arno, Alsharifi, Mohammed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187801/
https://ncbi.nlm.nih.gov/pubmed/21998693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025765
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