The Ectromelia Virus SPI-2 Protein Causes Lethal Mousepox by Preventing NK Cell Responses

Ectromelia virus (ECTV) is a natural pathogen of mice that causes mousepox, and many of its genes have been implicated in the modulation of host immune responses. Serine protease inhibitor 2 (SPI-2) is one of these putative ECTV host response modifier proteins. SPI-2 is conserved across orthopoxviru...

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Main Authors: Melo-Silva, Carolina R., Tscharke, David C., Lobigs, Mario, Koskinen, Aulikki, Wong, Yik Chun, Buller, R. Mark, Müllbacher, Arno, Regner, Matthias
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194934/
https://ncbi.nlm.nih.gov/pubmed/21849445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00256-11
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