The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-κB Sites in Proliferating Cells

The major immediate-early promoter (MIEP) region of human cytomegalovirus (HCMV) plays a critical role in the regulation of lytic and latent infections by integrating multiple signals supplied by the infecting virus, the type and physiological state of the host cell, and its extracellular surroundin...

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Hlavní autoři: Caposio, Patrizia, Luganini, Anna, Bronzini, Matteo, Landolfo, Santo, Gribaudo, Giorgio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863749/
https://ncbi.nlm.nih.gov/pubmed/20147408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02141-09
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