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The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-κB Sites in Proliferating Cells

The major immediate-early promoter (MIEP) region of human cytomegalovirus (HCMV) plays a critical role in the regulation of lytic and latent infections by integrating multiple signals supplied by the infecting virus, the type and physiological state of the host cell, and its extracellular surroundin...

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Autors principals: Caposio, Patrizia, Luganini, Anna, Bronzini, Matteo, Landolfo, Santo, Gribaudo, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863749/
https://ncbi.nlm.nih.gov/pubmed/20147408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02141-09
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