Sumoylation of the Epstein-Barr Virus BZLF1 Protein Inhibits Its Transcriptional Activity and Is Regulated by the Virus-Encoded Protein Kinase

The Epstein-Barr virus (EBV) immediate-early protein BZLF1 (Z) mediates the switch between latent and lytic EBV infection. Z not only activates early lytic viral gene transcription but also plays a direct role in lytic viral genome replication. Although a small fraction of Z is known to be sumoylate...

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Bibliografiske detaljer
Main Authors: Hagemeier, Stacy R., Dickerson, Sarah J., Meng, Qiao, Yu, Xianming, Mertz, Janet E., Kenney, Shannon C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863741/
https://ncbi.nlm.nih.gov/pubmed/20181712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02369-09
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