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Polyubiquitination of APOBEC3G Is Essential for Its Degradation by HIV-1 Vif

Proteasomal degradation of APOBEC3G is a critical step for human immunodeficiency virus type 1 (HIV-1) replication. However, the necessity for polyubiquitination of APOBEC3G in this process is still controversial. In this study, we showed that although macaque simian immunodeficiency virus (SIVmac)...

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Detalhes bibliográficos
Main Authors: Shao, Qiujia, Wang, Yudi, Hildreth, James E. K., Liu, Bindong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863731/
https://ncbi.nlm.nih.gov/pubmed/20147392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-09
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