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Mechanism of Mediator Recruitment by Tandem Gcn4 Activation Domains and Three Gal11 Activator-Binding Domains

Targets of the tandem Gcn4 acidic activation domains in transcription preinitiation complexes were identified by site-specific cross-linking. The individual Gcn4 activation domains cross-link to three common targets, Gal11/Med15, Taf12, and Tra1, which are subunits of four conserved coactivator comp...

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Bibliografiske detaljer
Main Authors: Herbig, Eric, Warfield, Linda, Fish, Lisa, Fishburn, James, Knutson, Bruce A., Moorefield, Beth, Pacheco, Derek, Hahn, Steven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863704/
https://ncbi.nlm.nih.gov/pubmed/20308326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01046-09
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