Activator Gcn4 Employs Multiple Segments of Med15/Gal11, Including the KIX Domain, to Recruit Mediator to Target Genes in Vivo

Mediator is a multisubunit coactivator required for initiation by RNA polymerase II. The Mediator tail subdomain, containing Med15/Gal11, is a target of the activator Gcn4 in vivo, critical for recruitment of native Mediator or the Mediator tail subdomain present in sin4Δ cells. Although several Gal...

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Detalhes bibliográficos
Main Authors: Jedidi, Iness, Zhang, Fan, Qiu, Hongfang, Stahl, Stephen J., Palmer, Ira, Kaufman, Joshua D., Nadaud, Philippe S., Mukherjee, Sujoy, Wingfield, Paul T., Jaroniec, Christopher P., Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Transcription, Chromatin, and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807301/
https://ncbi.nlm.nih.gov/pubmed/19940160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071589
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