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The Gcn5 Bromodomain of the SAGA Complex Facilitates Cooperative and Cross-tail Acetylation of Nucleosomes

Bromodomains are acetyl lysine binding modules found in many complexes that regulate gene transcription. In budding yeast, the coactivator complex SAGA (Spt-Ada-Gcn5-acetyl-transferase) predominantly facilitates transcription of stress-activated genes and requires the bromodomain of the Gcn5 subunit...

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Autori principali: Li, Shanshan, Shogren-Knaak, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666593/
https://ncbi.nlm.nih.gov/pubmed/19218239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809617200
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