Fluorescence Microscopy Demonstrates Enhanced Targeting of Telavancin to the Division Septum of Staphylococcus aureus

The cellular binding patterns of fluorescent conjugates of telavancin and vancomycin were evaluated in Staphylococcus aureus by fluorescence microscopy and ratio imaging analysis. Telavancin showed enhanced binding at the division septum compared to vancomycin. This result is consistent with observa...

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Main Authors: Lunde, Christopher S., Rexer, Charles H., Hartouni, Stephanie R., Axt, Sabine, Benton, Bret M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
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Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863671/
https://ncbi.nlm.nih.gov/pubmed/20176907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01609-09
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