Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus

The emergence and spread of multidrug-resistant gram-positive bacteria represent a serious clinical problem. Telavancin is a novel lipoglycopeptide antibiotic that possesses rapid in vitro bactericidal activity against a broad spectrum of clinically relevant gram-positive pathogens. Here we demonstr...

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Detalhes bibliográficos
Main Authors: Higgins, Deborah L., Chang, Ray, Debabov, DmitriV., Leung, Joey, Wu, Terry, Krause, Kevin M., Sandvik, Erik, Hubbard, JeffreyM., Kaniga, Koné, Schmidt, Donald E., Gao, Qiufeng, Cass, Robert T., Karr, Dane E., Benton, Bret M., Humphrey, Patrick P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549257/
https://ncbi.nlm.nih.gov/pubmed/15728913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1127-1134.2005
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