Pharmacokinetic-Pharmacodynamic Assessment of Faropenem in a Lethal Murine Bacillus anthracis Inhalation Postexposure Prophylaxis Model

There are few options for prophylaxis after exposure to Bacillus anthracis, especially in children and women of childbearing potential. Faropenem is a β-lactam in the penem subclass that is being developed as an oral prodrug, faropenem medoxomil, for the treatment of respiratory tract infections. Fa...

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Bibliografische gegevens
Hoofdauteurs: Gill, Stanley C., Rubino, Christopher M., Bassett, Jennifer, Miller, Lynda, Ambrose, Paul G., Bhavnani, Sujata M., Beaudry, Amber, Li, Jinfang, Stone, Kimberly Clawson, Critchley, Ian, Janjic, Nebojsa, Heine, Henry S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863661/
https://ncbi.nlm.nih.gov/pubmed/20145081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00737-08
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