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The Actinomycin Biosynthetic Gene Cluster of Streptomyces chrysomallus: a Genetic Hall of Mirrors for Synthesis of a Molecule with Mirror Symmetry

A gene cluster was identified which contains genes involved in the biosynthesis of actinomycin encompassing 50 kb of contiguous DNA on the chromosome of Streptomyces chrysomallus. It contains 28 genes with biosynthetic functions and is bordered on both sides by IS elements. Unprecedentedly, the clus...

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Detalhes bibliográficos
Main Authors: Keller, Ullrich, Lang, Manuel, Crnovcic, Ivana, Pfennig, Frank, Schauwecker, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863554/
https://ncbi.nlm.nih.gov/pubmed/20304989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01526-09
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