The Proline-Rich Region of Pneumococcal Surface Proteins A and C Contains Surface-Accessible Epitopes Common to All Pneumococci and Elicits Antibody-Mediated Protection against Sepsis

Pneumococcal surface protein A (PspA) and PspC of Streptococcus pneumoniae are surface virulence proteins that interfere with complement deposition and elicit protective immune responses. The C-terminal halves of PspA and PspC have some structural similarity and contain highly cross-reactive proline...

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Detalhes bibliográficos
Main Authors: Daniels, Calvin C., Coan, Patricia, King, Janice, Hale, Joanetha, Benton, Kimberly A., Briles, David E., Hollingshead, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863538/
https://ncbi.nlm.nih.gov/pubmed/20194601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01199-09
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