Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection

Immunization with the pneumococcal proteins pneumolysin (Ply), choline binding protein A (CbpA), or pneumococcal surface protein A (PspA) elicits protective responses against invasive pneumococcal disease in animal models. In this study, we used different mouse models to test the efficacy of a varie...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: Chen, Austen, Mann, Beth, Gao, Geli, Heath, Richard, King, Janice, Maissoneuve, Jeff, Alderson, Mark, Tate, Andrea, Hollingshead, Susan K., Tweten, Rodney K., Briles, David E., Tuomanen, Elaine I., Paton, James C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580740/
https://ncbi.nlm.nih.gov/pubmed/26245351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00293-15
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