Activated Alleles of the Schizosaccharomyces pombe gpa2(+) Gα Gene Identify Residues Involved in GDP-GTP Exchange

The Schizosaccharomyces pombe glucose/cyclic AMP (cAMP) signaling pathway includes the Gpa2-Git5-Git11 heterotrimeric G protein, whose Gpa2 Gα subunit directly binds to and activates adenylate cyclase in response to signaling from the Git3 G protein-coupled receptor. To study intrinsic and extrinsic...

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Bibliographic Details
Main Authors: Ivey, F. Douglas, Taglia, Francis X., Yang, Fan, Lander, Matthew M., Kelly, David A., Hoffman, Charles S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863420/
https://ncbi.nlm.nih.gov/pubmed/20139237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00010-10
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