Sck1 Negatively Regulates Gpa2-Mediated Glucose Signaling in Schizosaccharomyces pombe

Schizosaccharomyces pombe detects extracellular glucose via a G protein-mediated cyclic AMP (cAMP)-signaling pathway activating protein kinase A (PKA) and regulating transcription of genes involved in metabolism and sexual development. In this pathway, Gpa2 Gα binds to and activates adenylyl cyclase...

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Bibliographic Details
Main Authors: Mudge, Dayna K., Yang, Fan, Currie, Brian M., Kim, James M., Yeda, Kelly, Bashyakarla, Varoon K., Ivey, F. Douglas, Hoffman, Charles S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910974/
https://ncbi.nlm.nih.gov/pubmed/24297439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00277-13
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