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Mapping of Vps21 and HOPS Binding Sites in Vps8 and Effect of Binding Site Mutants on Endocytic Trafficking

Vps8 is a subunit of the CORVET tethering complex, which is involved in early-to-late endosome fusion. Here, we examine the role of Vps8 in membrane fusion at late endosomes in Saccharomyces cerevisiae. We demonstrate that Vps8 associates with membranes and that this association is independent of th...

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主要な著者: Pawelec, Agnes, Arsić, Janja, Kölling, Ralf
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863399/
https://ncbi.nlm.nih.gov/pubmed/20173035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00286-09
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