RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functional and mechanistic aspects in mammalian cells are less well defined. In this study, we re...

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Udgivet i:Sci Rep
Main Authors: Lin, Xiaosi, Yang, Ting, Wang, Shicong, Wang, Zhen, Yun, Ye, Sun, Lixiang, Zhou, Yunhe, Xu, Xiaohui, Akazawa, Chihiro, Hong, Wanjin, Wang, Tuanlao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250914/
https://ncbi.nlm.nih.gov/pubmed/25445562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07282
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