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Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt

Two related multisubunit tethering complexes promote endolysosomal trafficking in all eukaryotes: Rab5-binding CORVET that was suggested to transform into Rab7-binding HOPS. We have previously identified miniCORVET, containing Drosophila Vps8 and three shared core proteins, which are required for en...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lőrincz, Péter, Kenéz, Lili Anna, Tóth, Sarolta, Kiss, Viktória, Varga, Ágnes, Csizmadia, Tamás, Simon-Vecsei, Zsófia, Juhász, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592680/
https://ncbi.nlm.nih.gov/pubmed/31194677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45631
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