Aggregation of Streptococcus pneumoniae by a Pneumococcal Capsular Polysaccharide-Specific Human Monoclonal IgM Correlates with Antibody Efficacy In Vivo

Acquired antibody immunity to Streptococcus pneumoniae (pneumococcus) has been linked to serotype (ST)-specific opsonic antibodies to the relevant pneumococcal capsular polysaccharide (PPS) that mediate protection by enhancing the bactericidal effect of host phagocytes. Despite the well-recognized r...

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Autores principales: Fabrizio, Kevin, Manix, Catherine, Guimaraes̃, Allan J., Nosanchuk, Joshua D., Pirofski, Liise-anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Microbial Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863372/
https://ncbi.nlm.nih.gov/pubmed/20200186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00410-09
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