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Glucose Suppression of Glucagon Secretion: METABOLIC AND CALCIUM RESPONSES FROM α-CELLS IN INTACT MOUSE PANCREATIC ISLETS

Glucagon is released from α-cells present in intact pancreatic islets at glucose concentrations below 4 mm, whereas higher glucose levels inhibit its secretion. The mechanisms underlying the suppression of α-cell secretory activity are poorly understood, but two general types of models have been pro...

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Главные авторы: Le Marchand, Sylvain J., Piston, David W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863245/
https://ncbi.nlm.nih.gov/pubmed/20231269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069195
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