A carregar...

Mutant p53-induced Up-regulation of Mitogen-activated Protein Kinase Kinase 3 Contributes to Gain of Function

Mitogen-activated protein kinase kinase 3 (MAP2K3) is a member of the dual specificity kinase group. Growing evidence links MAP2K3 to invasion and tumor progression. Here, we identify MAP2K3 as a transcriptional target of endogenous gain-of-function p53 mutants R273H, R175H, and R280K. We show that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gurtner, Aymone, Starace, Giuseppe, Norelli, Giuseppe, Piaggio, Giulia, Sacchi, Ada, Bossi, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863202/
https://ncbi.nlm.nih.gov/pubmed/20223820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094813
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!