The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation

The newly discovered p73 gene encodes a nuclear protein that has high homology with p53. Furthermore, ectopic expression of p73 in p53(+/+) and p53(−/−) cancer cells recapitulates some of the biological activities of p53 such as growth arrest, apoptosis, and differentiation. p73(−/−)-deficient mice...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Fontemaggi, Giulia, Gurtner, Aymone, Strano, Sabrina, Higashi, Yujiro, Sacchi, Ada, Piaggio, Giulia, Blandino, Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC100009/
https://ncbi.nlm.nih.gov/pubmed/11713281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8461-8470.2001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky