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The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation
The newly discovered p73 gene encodes a nuclear protein that has high homology with p53. Furthermore, ectopic expression of p73 in p53(+/+) and p53(−/−) cancer cells recapitulates some of the biological activities of p53 such as growth arrest, apoptosis, and differentiation. p73(−/−)-deficient mice...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC100009/ https://ncbi.nlm.nih.gov/pubmed/11713281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8461-8470.2001 |
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