β-Arrestins Scaffold Cofilin with Chronophin to Direct Localized Actin Filament Severing and Membrane Protrusions Downstream of Protease-activated Receptor-2

Protease-activated receptor-2 (PAR-2) mediates pro-inflammatory signals in a number of organs, including enhancing leukocyte recruitment to sites of injury and infection. At the cellular level, PAR-2 promotes activation of the actin filament-severing protein cofilin, which is crucial for the reorgan...

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Bibliografiske detaljer
Main Authors: Zoudilova, Maria, Min, Jungah, Richards, Heddie L., Carter, David, Huang, Timothy, DeFea, Kathryn A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863192/
https://ncbi.nlm.nih.gov/pubmed/20207744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055806
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