JNK-mediated Phosphorylation of Cdc25C Regulates Cell Cycle Entry and G(2)/M DNA Damage Checkpoint

c-Jun NH(2)-terminal Kinases (JNKs) play a central role in the cellular response to a wide variety of stress signals. After their activation, JNKs induce phosphorylation of substrates, which control proliferation, migration, survival, and differentiation. Recent studies suggest that JNKs may also pl...

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Bibliographic Details
Main Authors: Gutierrez, Gustavo J., Tsuji, Toshiya, Cross, Janet V., Davis, Roger J., Templeton, Dennis J., Jiang, Wei, Ronai, Ze'ev A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863176/
https://ncbi.nlm.nih.gov/pubmed/20220133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.121848
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