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Public TCR use by HSV-2-specific human CD8 CTL

Recombination of germ-line TCR alpha and beta genes generates polypeptide receptors for MHC-peptide. Antigen exposure during long-term herpes simplex infections may shape the T-cell repertoire over time. We investigated the CD8 T-cell response to HSV-2 in chronically infected individuals by sequenci...

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Detalhes bibliográficos
Main Authors: Dong, Lichun, Li, Penny, Oenema, Tjitske, McClurkan, Christopher L., Koelle, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863070/
https://ncbi.nlm.nih.gov/pubmed/20139278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903622
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