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A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice

Humans with L1 cell adhesion molecule (L1CAM) mutations exhibit X-linked hydrocephalus, as well as other severe neurological disorders. L1-6D mutant mice, which are homozygous for a deletion that removes the sixth immunoglobulin-like domain of L1cam, seldom display hydrocephalus on the 129/Sv backgr...

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Detalhes bibliográficos
Main Authors: Tapanes-Castillo, Alexis, Weaver, Eli J., Smith, Robin P., Kamei, Yoshimasa, Caspary, Tamara, Hamilton-Nelson, Kara L., Slifer, Susan H., Martin, Eden R., Bixby, John L., Lemmon, Vance P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863031/
https://ncbi.nlm.nih.gov/pubmed/19565280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-009-0203-3
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