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The role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development
Mutations in the human L1CAM gene cause X-linked Hydrocephalus and MASA syndrome. In vitro studies have shown the L1 cytoplasmic domain (L1CD) is involved in L1 trafficking, neurite branching, signaling, and interactions with the cytoskeleton. L1cam knock-out (L1(KO)) mice have hydrocephalus, a smal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158433/ https://ncbi.nlm.nih.gov/pubmed/20127821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.22267 |
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