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Brain development in mice lacking L1–L1 homophilic adhesion

A new mouse line has been produced in which the sixth Ig domain of the L1 cell adhesion molecule has been deleted. Despite the rather large deletion, L1 expression is preserved at normal levels. In vitro experiments showed that L1–L1 homophilic binding was lost, along with L1-α5β1 integrin binding....

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Detalhes bibliográficos
Main Authors: Itoh, Kyoko, Cheng, Ling, Kamei, Yoshimasa, Fushiki, Shinji, Kamiguchi, Hiroyuki, Gutwein, Paul, Stoeck, Alexander, Arnold, Bernd, Altevogt, Peter, Lemmon, Vance
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172083/
https://ncbi.nlm.nih.gov/pubmed/15067019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312107
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