Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart

Previously, we demonstrated (17) that 11,12- and 14,15-epoxyeicosatrienoic acids (EETs) produce marked reductions in myocardial infarct size. Although it is assumed that this cardioprotective effect of the EETs is due to a specific interaction with a membrane-bound receptor, no evidence has indicate...

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Main Authors: Gross, Garrett J., Gauthier, Kathryn M., Moore, Jeannine, Falck, John R., Hammock, Bruce D., Campbell, William B., Nithipatikom, Kasem
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863006/
https://ncbi.nlm.nih.gov/pubmed/18441205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00186.2008
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