Adaptive Evolution Hotspots at the GC-Extremes of the Human Genome: Evidence for Two Functionally Distinct Pathways of Positive Selection

We recently reported that the human genome is ‘‘splitting” into two gene subgroups characterised by polarised GC content (Tang et al, 2007), and that such evolutionary change may be accelerated by programmed genetic instability (Zhao et al, 2008). Here we extend this work by mapping the presence of...

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Bibliographic Details
Main Authors: Tang, Clara S. M., Epstein, Richard J.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862947/
https://ncbi.nlm.nih.gov/pubmed/20454629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/856825
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