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ABELSON VIRUS TRANSFORMATION PREVENTS TRAIL EXPRESSION BY INHIBITING FOXO3A AND NF-κB
The Abelson Murine Leukemia Virus (A-MuLV) encodes v-Abl, an oncogenic form of the ubiquitous cellular non-receptor tyrosine kinase, c-Abl. A-MuLV specifically transforms murine B cell precursors both in vivo and in vitro. Inhibition of v-Abl by addition of the small molecule inhibitor STI-571 cause...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862835/ https://ncbi.nlm.nih.gov/pubmed/20213318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-010-0029-8 |
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