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Decrease in PTEN and increase in Akt expression and neuron size in aged rat spinal cord

PTEN is a tumor suppressor gene known to play an important role in the regulation of cell size. In this study we compared PTEN expression in the spinal cord of young (5 mo.) versus aged (32 mo.) female rats and correlated them with alterations in neuron size and morphology in the same animals. Total...

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Autors principals: Rodrigues De Amorim, Miguel Augusto, Garcia-Segura, Luis Miguel, Goya, Rodolfo Gustavo, Portiansky, Enrique Leo
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862775/
https://ncbi.nlm.nih.gov/pubmed/20347952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2010.03.015
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