Neuronal Ablation of IKK2 Decreases Lesion Size and Improves Functional Outcome after Spinal Cord Injury in Mice

Nuclear factor-kappa B (NF-κB) is a key modulator of inflammation and secondary injury responses in neurodegenerative disease, including spinal cord injury (SCI). Inhibition of astroglial NF-κB reduces inflammation, enhances oligodendrogenesis and improves functional recovery after SCI, however the...

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Detalhes bibliográficos
Publicado no:JSM Neurosurg Spine
Main Authors: Ellman, Ditte Gry, Novrup, Hans Gram, Jørgensen, Louise Helskov, Lund, Minna Christiansen, Yli-Karjanmaa, Minna, Madsen, Pernille Marie, Vienhues, Jonas Heinrich, Dursun, Safinaz, Bethea, John R., Lykke-Hartmann, Karin, Brambilla, Roberta, Lambertsen, Kate Lykke
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051723/
https://ncbi.nlm.nih.gov/pubmed/30035210
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