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ADAM8 is a negative regulator of retinal neovascularization and of the growth of heterotopically injected tumor cells in mice

ADAM8 is a member of the “a disintegrin and metalloproteinase” (ADAM) family of membrane-anchored metalloproteinases. ADAM8-deficient mice have no evident spontaneous developmental or pathological defects, and little is currently known about the role of ADAM8 in disease. Here, we investigated the co...

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Autors principals: Guaiquil, Victor H., Swendeman, Steven, Zhou, Wenhui, Guaiquil, Patricio, Weskamp, Gisela, Bartsch, Jörg W., Blobel, Carl P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862722/
https://ncbi.nlm.nih.gov/pubmed/20119708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0591-8
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