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PHARMACOKINETIC/PHARMACODYNAMIC MODELING OF THE ANTIRETROVIRAL ACTIVITY OF THE CCR5 ANTAGONIST VICRIVIROC IN TREATMENT EXPERIENCED HIV-INFECTED SUBJECTS (ACTG PROTOCOL 5211)
OBJECTIVE: This sub-study of ACTG Protocol 5211 explored the relationship between antiretroviral effect and plasma concentrations of vicriviroc, an investigational CCR5-antagonist for HIV infection. Eighty-six treatment-experienced subjects failing their current antiretroviral regimens were randomiz...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862681/ https://ncbi.nlm.nih.gov/pubmed/20071999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181c9caac |
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