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Decreased Osteoclastogenesis and High Bone Mass in Mice with Impaired Insulin Clearance Due to Liver-Specific Inactivation to CEACAM1

Type 2 diabetes is associated with normal-to-higher bone mineral density (BMD) and increased rate of fracture. Hyperinsulinemia and hyperglycemia may affect bone mass and quality in the diabetic skeleton. In order to dissect the effect of hyperinsulinemia from the hyperglycemic impact on bone homeos...

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Detalhes bibliográficos
Main Authors: Huang, S., Kaw, M., Harris, M.T., Ebraheim, N., McInerney, M.F., Najjar, S.M., Lecka-Czernik, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862391/
https://ncbi.nlm.nih.gov/pubmed/20044046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.12.020
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