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Dissection of genetically complex traits with extremely large pools of yeast segregants

Most heritable traits, including many human diseases 1, are caused by multiple loci. Studies in both humans and model organisms, such as yeast, have failed to detect a large fraction of the loci that underlie such complex traits 2,3. A lack of statistical power to identify multiple loci with small e...

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Detalhes bibliográficos
Main Authors: Ehrenreich, Ian M., Torabi, Noorossadat, Jia, Yue, Kent, Jonathan, Martis, Stephen, Shapiro, Joshua A., Gresham, David, Caudy, Amy A., Kruglyak, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862354/
https://ncbi.nlm.nih.gov/pubmed/20393561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08923
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