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Chimeric Adenoviral Vectors Incorporating a Fiber of Human Adenovirus 3 Efficiently Mediate Gene Transfer into Prostate Cancer Cells

BACKGROUND: We have developed a range of adenoviral (Ad) vectors based on human adenovirus serotype 5 (HAdV-5) displaying the fiber shaft and knob domains of species B viruses (HAdV-3, HAdV-11, or HAdV-35). These species B Ads utilize different cellular receptors than HAdV-5 for infection. We evalua...

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Detalhes bibliográficos
Main Authors: Murakami, Miho, Ugai, Hideyo, Belousova, Natalya, Pereboev, Alexander, Dent, Paul, Fisher, Paul B., Everts, Maaike, Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862273/
https://ncbi.nlm.nih.gov/pubmed/19902467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21070
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