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Linking Well-Tempered Metadynamics Simulations with Experiments

Linking experiments with the atomistic resolution provided by molecular dynamics simulations can shed light on the structure and dynamics of protein-disordered states. The sampling limitations of classical molecular dynamics can be overcome using metadynamics, which is based on the introduction of a...

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Hlavní autoři: Barducci, Alessandro, Bonomi, Massimiliano, Parrinello, Michele
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862196/
https://ncbi.nlm.nih.gov/pubmed/20441734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.033
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