Tryptophan as a Molecular Shovel in the Glycosyl Transfer Activity of Trypanosoma cruzi Trans-sialidase

Molecular dynamics investigations into active site plasticity of Trypanosoma cruzi trans-sialidase, a protein implicated in Chagas disease, suggest that movement of the Trp(312) loop plays an important role in the enzyme's sialic acid transfer mechanism. The observed Trp(312) flexibility equate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mitchell, Felicity L., Miles, Steven M., Neres, João, Bichenkova, Elena V., Bryce, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Biophysical Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862183/
https://ncbi.nlm.nih.gov/pubmed/20441732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker