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Counter-Intuitive Stochastic Behavior of Simple Gene Circuits with Negative Feedback

It has often been taken for granted that negative feedback loops in gene regulation work as homeostatic control mechanisms. If one increases the regulation strength a less noisy signal is to be expected. However, recent theoretical studies have reported the exact contrary, counter-intuitive observat...

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Detalhes bibliográficos
Main Authors: Marquez-Lago, Tatiana T., Stelling, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862162/
https://ncbi.nlm.nih.gov/pubmed/20441737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.018
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